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ADB5-Plus™ (Biotics Research)

The body needs to maintain a stable internal environment to survive, and the adrenal glands play a crucial role in this by releasing specific hormones like adrenaline, noradrenaline, and cortisol in response to stress. These hormones trigger various physiological effects, such as an increased heart rate and heightened alertness, helping the body cope with stress. However, constant or excessive stress can lead to negative consequences like adrenal gland enlargement, digestive issues, and immune dysfunction, ultimately causing bodily harm.

Stress-related illnesses are common and can present in various forms, including physical stress from overwork, chemical stress from pollutants and poor diet, thermal stress from extreme temperatures, and emotional and mental stress. Adrenal fatigue, a condition often misdiagnosed as chronic fatigue or other illnesses, is prevalent but frequently goes undiagnosed. The adrenal glands, vital for many bodily functions due to the hormones they produce, significantly impact overall health and well-being. Adrenal dysfunction can lead to serious conditions like Addison's disease or general adrenal fatigue, affecting metabolism, cardiovascular health, and sexual desire. Nutrients such as vitamins, minerals, and botanicals can support adrenal health and help restore their function.

Vitamins for Adrenal Support

Vitamin C:

The adrenal glands have a high concentration of vitamin C, about 100 times more than in the blood. This makes them very sensitive to a lack of vitamin C. Vitamin C helps make certain stress-related hormones. When the body is stressed, the adrenal glands release more vitamin C along with cortisol. Factors like stress, fever, infections, smoking, and drinking alcohol can lower vitamin C levels quickly. People under stress often need more vitamin C.

Thiamin (B1):

Thiamin, as a coenzyme, is crucial for glucose metabolism inside cells, which is important for adrenal function because blood sugar fluctuations are a symptom of adrenal issues. It helps metabolize carbohydrates and is vital for energy production. A lack of thiamin can slow down or block these processes, affecting multiple enzymes, particularly those involved in carbohydrate metabolism.

Riboflavin (B2):

Riboflavin is a key part of the coenzymes FAD and FMN. These are necessary for energy production and red blood cell formation. Adrenal and thyroid problems can impair riboflavin conversion. A deficiency can increase oxidative stress and affect energy transfer, metabolism, antibody production, and growth hormone regulation.

Niacin (B3):

Niacin is essential for the coenzymes NAD and NADP, crucial for energy production and DNA repair. It's important for insulin response and helps manage hypoglycemic symptoms associated with adrenal issues. A lack of niacin can lead to skin changes and nervous system problems.

Vitamin B6:

Vitamin B6 acts as a coenzyme in over 100 reactions related to metabolism and health. It supports lipid metabolism and energy production, and its deficiency can lead to decreased mental sharpness, which is common in adrenal dysfunction. It also helps convert tryptophan to niacin and serotonin, and tyrosine to dopamine, which are crucial for adrenal hormone production.

Vitamin B12:

Vitamin B12 is essential for DNA synthesis and overall cell health. Its deficiency can cause fatigue and affect neurotransmitter synthesis, leading to cognitive issues. Supplementing B12 can help improve mental acuity and support adrenal function.


Folate is vital for DNA synthesis and reducing homocysteine levels. A lack of folate can cause weakness, depression, and nerve disorders, which can affect overall health and adrenal function.

Pantothenic Acid (B5):

Pantothenic acid is important for metabolizing carbohydrates, fats, and proteins. It's essential for neurotransmitter production and energy cycles. Its deficiency can lead to adrenal gland problems and difficulties handling stress, hence it's sometimes called the "anti-stress" vitamin.

Minerals for Adrenal Support


Iron is crucial for hemoglobin in red blood cells, which transports oxygen. It's also a cofactor for neurotransmitter synthesis. Iron deficiency can impair adrenal function and energy metabolism.


Magnesium is involved in over 300 metabolic reactions, including energy production. A deficiency can cause muscle spasms and neuromuscular symptoms. It's necessary for adrenal hormone production and stress recovery, and its absorption decreases with age.


Zinc is essential for enzyme function and adrenal health. A deficiency can affect enzyme activity and increase stress responses. Supplementing zinc can improve adrenal function and reduce stress-related damage.


Manganese is a component of mitochondrial enzymes that protect cells from oxidative stress. It's crucial for carbohydrate, amino acid, and cholesterol metabolism. Manganese deficiency can impair these functions and increase stress.


Copper plays a role in oxidation-reduction reactions and is a component of enzymes involved in cellular energy production. It's vital for adrenal support and overall health.

Botanicals for Adrenal Support

Rhodiola rosea:

This plant has been used for centuries to reduce anxiety, depression, and fatigue. It's known as an adaptogen that helps the body handle stress.

Tyrosinase (from mushroom):

Tyrosinase is rich in amino acids and helps produce dopamine, noradrenaline, and adrenaline, which are crucial for adrenal function.

Other Supportive Components

Malic Acid:

Malic acid is essential for the citric acid cycle and energy production. A deficiency can cause physical exhaustion. It's also involved in detoxification processes.

Citrus Bioflavonoids:

These antioxidants help maintain high vitamin C levels in the adrenal glands, supporting their function during stress.

N-acetyl-L-cysteine (NAC):

NAC is a powerful antioxidant that helps protect cells from oxidative damage during stress.


Choline is essential for cell membrane integrity and neurotransmitter production, supporting overall cell health and function.

Superoxide Dismutase and Catalase:

These antioxidants help reduce oxidative damage and support adrenal health.

Glandular Support

Adrenal Gland Concentrate (porcine), Lamb Pituitary/Hypothalamus Complex (ovine), Parotid Tissue (bovine):

These glandular components provide raw materials and chemical messengers that support adrenal function, helping to relieve stress on the adrenal glands and promote recovery.


For supporting adrenal health, a variety of vitamins, minerals, botanicals, and glandular components play crucial roles. Vitamin C, B vitamins (B1, B2, B3, B6, B12, and B5), iron, magnesium, zinc, manganese, copper, and malic acid all contribute to energy production, stress response, and overall adrenal function.

Botanicals like Rhodiola rosea and components like tyrosinase from mushrooms aid in managing stress and supporting neurotransmitter production. Antioxidants, including citrus bioflavonoids, NAC, and enzymes like superoxide dismutase and catalase, help reduce oxidative stress.

Glandular extracts from adrenal, pituitary, hypothalamus, and parotid tissues provide additional support by supplying essential materials and messengers. Together, these elements help restore and maintain healthy adrenal function, which is vital for coping with stress and promoting overall health.

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Jones Chiropractic is a self-pay clinic. We do not accept insurance, but we do accept all forms of payments including FSA/HSA payments at time of service.

Please Note: Some of our services and products have not undergone evaluation or approval by the FDA. It is always advised that you consult with a licensed healthcare provider, including our doctors, before considering any new treatment. Medical Disclaimer.

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